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InfoGenomeR: Integrative reconstruction of cancer genome karyotypes
InfoGenomeR is the Integrative Framework for Genome Reconstruction that uses a breakpoint graph to m...l the connectivity among genomic segments at the genome-wide scale. InfoGenomeR integ...the optimal breakpoint graph representing cancer geno...1096 days ago
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Scaffolding of a bacterial genome using MinION nanopore sequencing
Second generation sequencing has revolutionized genomic studies. However, most genomes contain repeated DNA elements that are longer than the read lengths achievable with typical sequencers,...3224 days ago
Assembly and diploid architecture of an individual human genome via single-molecule technologies
The research work shows that it is now possible to integrate single-molecule and high-throughput sequence data to generate de novo assembled genomes that approach reference quality. https://www.geno...3220 days ago