BOL

ncbi.github.io - Magic-BLAST is a tool for mapping large next-generation RNA or DNA sequencing runs against a whole genome or transcriptome. Each alignment optimizes a composite score, taking into account simultaneously the two reads of a pair, and in case of...

blast.ncbi.nlm.nih.gov - ElasticBLAST is a new way to BLAST large numbers of queries, faster and on the cloud. Here are the top three reasons you should use ElasticBLAST: 1. ElasticBLAST can handle much LARGER queries!  ElasticBLAST can search query...

github.com - TwinBLAST is a web-based tool for viewing 2 BLAST reports simultaneouslyside-by-side. It uses ExtJS (www.sencha.com/products/extjs/) to provide 2independently scrollable panels. BioPerl (www.bioperl.org) is used to indexraw BLAST reports and...

Genome sequencing projects have enormous potential for benefiting human endeavors. However, just as acquiring a language's vocabulary does not enable one to speak it, databases that list the amino acid composition of proteins do not directly tell us...

The BLAST+ 5 (Basic Local Alignment Search Tool) update has introduced several key enhancements aimed at improving performance, user experience, and compatibility with evolving genomic data standards. Here are the major updates:

wlcb.oit.uci.edu - Circos visualization https://wlcb.oit.uci.edu/modules/index.html

Xpandomer in a single drop reaction to sequence an entire human genome 1000X over.

github.com - methylKit is an R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing. The package is designed to deal with sequencing data from RRBS and its variants, but also target-capture methods such as Agilent...

http://kaiju.binf.ku.dk/ - Kaiju is a program for the taxonomic classification of metagenomic high-throughput sequencing reads. Each read is directly assigned to a taxon within the NCBI taxonomy by comparing it to a reference database containing microbial and viral protein...

Structural variation caller tools using long reads