Dahak: benchmarking and containerization of tools for analysis of complex non-clinical metagenomes.
Dahak is a software suite that integrates state-of-the-art open source tools for metagenomic analyses. Tools in the dahak software suite will perform various steps in m...1500 days ago
RefKA: A fast and efficient long-read genome assembly approach for large and complex genomes
RefKA, a reference-based approach for long read genome assembly. This approach relies on breaking up a closely related reference genome into bins, aligning k-mers unique to each bin with PacBio reads, and then assembling each bin in parallel followed by a final bin-stitching step.1478 days ago
HNADOCK: a nucleic acid docking server for modeling RNA/DNA–RNA/DNA 3D complex structures
The HNADOCK server is to predict the binding complex structure between two nucleic acid molecules through a hierarchical docking algorihtm of an FFT-based global search strategy and a...1443 days ago
1409 days ago
RosettaAntibodyDesign (RAbD): A general framework for computational antibody design
...r the run to their project needs. The algorithm is meant to sample the diverse sequence, structure, and binding space of an antibody-antigen complex. It can be used for a mu...1336 days ago
Hifiasm: a haplotype-resolved assembler for accurate Hifi reads
...vo assembler for PacBio Hifi reads. It can assemble a human genome in several hours and works with the California redwood genome, one of the most complex genomes sequenced so far. Hif...1241 days ago
Luigi: a Python package that helps you build complex pipelines of batch jobs.
Luigi is a Python (3.6, 3.7, 3.8, 3.9 tested) package that helps you build complex pipelines of batch jobs. It handles dependency resolution, workflow management, visualization, handl...1059 days ago
oGNM:Conformational dynamics based on contact topology in a coarse-grained presentation
...re can be crystal contacts defined in structures solved by x-ray crystallography, a protein in homo-/hetero-dimers, a part of a protein complex, the DNA in complexed with transcription factors,...852 days ago
The complete sequence of a human genome
The completed regions include all centromeric satellite arrays, recent segmental duplications, and the short arms of all five acrocentric chromosomes, unlocking these complex regions of the genome to variational and functional studies.778 days ago
420 days ago